Frank Strong earned his bachelor's and legal degrees from Yale University, in 1929 and 1934, respectively. He was a member of the law faculty at University of Iowa College of Law from 1934 to 1937. While at Iowa, he served as faculty advisor to the Iowa Law Review and oversaw its transition to a student-run publication.
After leaving Iowa, he taught law at Ohio State University College of Law. Ohio State University's annual Judges' Day is named the Frank R. Strong Forum in honor of Strong, who also served as its dean from 1952 to 1965. In 1965, he moved to University of North Carolina School of Law, where he spent the rest of his career. His work focused on constitutional law. He died in 2001.